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Author

Yi-Mu Fang

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Open access Oct 2026

CD147+ Cancer-Associated Fibroblasts Promote PD-L1 Expression in Hepatocellular Carcinoma via TIMP2/MMP2/IL-6 Signaling.

This study delineates a novel CAF-driven immunosuppressive pathway in HCC, where CD147+ CAFs enhance tumor cell PD-L1 expression and susceptibility to immune checkpoint blockade via a TIMP2/MMP2/IL-6 axis.

Yi-Fei Wang, Bo-Wei Lv, Xiao-Jing Su et al. · 0 citations

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