Author

Yi-Nan Liu

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Aug 2026

Necroptosis Activates NLRP3 Inflammasome to Drive Necroinflammation in T-2 Toxin-induced Cartilage Damage.

As a highly toxic mycotoxin present in contaminated food sources, T-2 toxin disrupts skeletal development by inducing cartilage injury. However, the underlying molecular mechanisms remain unclear. Following four weeks of gavage administration of T-2 toxin (200 ng/g body weight/day) to three-week-old male C57BL/6 mice,...

Meng Zhang, Jing Tian, Yi-Nan Liu et al. · Food and Chemical Toxicology · 0 citations

Review Open access Aug 2026

Lipid droplets as redox-active organelles after spinal cord injury: lipid peroxidation, mitochondrial dysfunction, and neuroinflammation

Abstract Objectives Spinal cord injury (SCI) causes myelin breakdown and membrane disruption, leading to the release and redistribution of cholesterol, fatty acids, and other lipids within the lesion. The resulting disruption of lipid homeostasis can promote sustained lipid peroxidation, neuroinflammation, and repair f...

Yi-Chen Zhang, Jie Li, Yi-Nan Liu et al. · Redox Report · 0 citations