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Yi-Ni Zhuang

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Open access Sep 2026

Carrier-free nanomodulators reprogramming acetate metabolism for cancer photo-immunotherapy via c-Myc inhibition-induced closed-loop regulatory circuit

Non-small cell lung cancer (NSCLC) remains difficult to cure owing to therapy resistance and immune evasion that limits durable therapeutic responses. Here, we report a carrier-free nanoregulator (CE NPs) formed by co-assembling chlorin e6 (Ce6) with a covalent c-Myc inhibitor (EN4), enabling photo-immunotherapy that c...

Jian-Wei Zhu, Dan-Ming Dong, Jia-Yue Xu et al. · 0 citations

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