Author

Yi-Ning Jia

2 papers indexed here

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Oct 2026

Enantioselective Synthesis of Chiral 3-Substituted Tetrahydroquinolines via a Pd-Catalyzed C–C Cleavage/C–C Coupling Sequence

A palladium-catalyzed asymmetric synthesis of 3-substituted tetrahydroquinolines (THQs) through a C–C cleavage/C–C coupling sequence has been developed. By employing Pd(OAc)2/Josiphos L7 as the catalyst, an array of chiral tetrahydroquinolines bearing a C3-ketone pendant was afforded in good to excellent yields and e...

Cheng-Yu Li, Xiao-Jing Liu, Zhen-Ting Mao et al. · Organic Letters · 0 citations

Aug 2026

Asymmetric Allylic Dearomatization of Quinolines via Dynamic Ligand Exchange.

The strong coordination of quinolines to transition metals typically interferes with chiral catalysts, restricting their use in asymmetric synthesis. Here, we harness this challenging property as a stereocontrol element through the integration of dynamic ligand exchange with designed hydrogen-bonding interactions betwe...

Jianfeng Xu, Li Zhou, Xue-Pei Bai et al. · Angewandte Chemie · 0 citations