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Yi-Ning Jiang

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Open access Oct 2026

Low‐Density Lipoprotein Receptor‐Targeted Biomimetic Nanoplatform Suppresses Glioblastoma Stemness and Remodels Antitumor Immunity via Dual Metabolic Disruption

ABSTRACT Glioblastoma (GBM) remains one of the most lethal malignancies because durable tumor control is constrained by limited brain‐tumor drug exposure, metabolic plasticity, stem‐like tumor states, and an immunosuppressive microenvironment. We developed apolipoprotein B fragment‐decorated nanoparticles co‐loaded wit...

Yi-Ning Jiang, Wen-Zhuo Yang, Wen-Ting Cheng et al. · 0 citations
Aug 2026

Surface-engineered GE11-functionalized exosomes for EGFR-targeted peonidin delivery and suppression of SNAI1-mediated epithelial-mesenchymal transition in glioma.

Glioblastoma is a highly aggressive and invasive brain tumor with poor prognosis, largely due to its rapid progression, epithelial-mesenchymal transition (EMT)-mediated invasiveness, and resistance to conventional therapies. Herein, the surface-engineered exosomal nanoplatform for targeted glioma therapy is functionali...

Yang Bai, Yuexiang Jin, Yi-Ning Jiang et al. · 0 citations

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