Open access
Jul 2026
SMAD5 as a novel susceptibility gene for congenital patent ductus arteriosus.
It is indicated that SMAD5 haplo-insufficient variants contribute to PDA in humans, which sheds more light on the genetic architecture of PDA and implies a potential target for genetic counseling and individualized medicine of PDA in a subgroup of patients.
Hong Zhang, Xiao-Qing Hu, Yan-Jie Li et al.
· Scientific Reports · 0 citations