Yi-Shan Cai

Research Progress on the Molecular Pathways Regulating Mammalian Sleep–Wake Rhythms

The mammalian brain governs the timing of sleep and wakefulness with considerable precision, yet the mechanism underlying this timing is not a single switch. Work over the past two decades has uncovered a layered molecular architecture in which neurotransmitter systems, neuropeptide signaling, and circadian clock genes...