The intestinal microbiota has emerged as a crucial regulator of host physiological functions, significantly influencing various forms of regulated cell death (RCD). Among these, pyroptosis and ferroptosis play pivotal roles in immune regulation, metabolic homeostasis, and disease progression. The gut microbiota modulat...
Yi Shen, Yun-Feng Zhou, Yang Yuan et al.· Frontiers in Microbiology· 0 citations
Circulating tumor DNA (ctDNA), a core component of liquid biopsy, demonstrates significant potential in the field of neoadjuvant therapy for solid tumors. This review systematically examines the role of ctDNA across the pre-, intra-, and post-neoadjuvant treatment phases, with a focus on its value in predicting therape...
Xue-Qin Huang, Yuan-He Deng, Yi Shen· Frontiers in Oncology· 0 citations
This review systematically summarizes the molecular regulatory mechanisms of pyroptosis, encompassing classical and non-classical inflammasome pathways, activation and modulation of gasdermin proteins, and the intricate signaling networks involved.
Yi Shen, Qiang-Qiang Zheng, Yang Yuan et al.· Frontiers in Cell and Develo...· 0 citations
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