Lensless imaging offers a new route to substantially alleviate the shackle of space-bandwidth-product (SBP) on conventional optical microscopes, thus high resolution and wide field-of-view (FOV) can be more easily achieved simultaneously. A series of lensless imaging methods have taken their place in chemical bioimagin...
This study represents the first real-time observation of a concentration-dependent transition in ROS scavenging dynamics in single microglial cells, providing a previously inaccessible view of neuroinflammatory redox regulation under undisturbed physiological conditions.
The limit of quantification is improved to the fmol level in native biological environments, enabling the direct identification of neoantigens from as few as 5000 cells within 30 min, and the identification of a native Epstein–Barr virus-associated neoantigen is demonstrated.
Yan Gao, Yun-Ze Wu, Jie Jiang et al.· Journal of the American Chem...· 0 citations
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