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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

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Yi-Ting Tu

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Open access Sep 2026

Narirutin mitigates osteoarthritis by targeting USP15 to promote KEAP1 degradation and suppress chondrocyte ferroptosis.

BACKGROUND Osteoarthritis (OA) is a prevalent degenerative joint disease characterized by progressive cartilage degeneration and joint dysfunction, for which effective therapeutic options remain limited. Increasing evidence suggests that ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxi...

Xiang-Cheng Zhang, Su-Yu Ying, Yi-Ting Tu et al. · 0 citations
Sep 2026

Trans-zeatin suppresses osteoclastogenesis and prevents estrogen deficiency-induced bone loss by modulating Nrf2-mediated redox homeostasis and AKT signaling.

Postmenopausal osteoporosis (PMOP) is a metabolic bone disorder driven by excessive osteoclast (OC) activity, but current therapies are limited by adverse effects. Trans-zeatin (TZ), a naturally occurring plant cytokinin with antioxidant properties, has not been investigated in bone metabolism. Here, we show that TZ su...

Yong Xiao, Qi-Chen Lu, Miao-Miao Shi et al. · 0 citations

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