Disrupted blood-brain barrier maturation links congenital heart diseases to hippocampal injury: Insights from a translational neonatal mouse model.
BACKGROUND Neurodevelopmental impairment is the most common non-cardiac morbidity in children with congenital heart diseases (CHDs), yet its pathogenic mechanisms remain poorly understood due to a lack of disease-specific animal models. Right ventricular outflow tract obstruction (RVOTO) is a prevalent CHD lesion. We i...