Open access
2026
Linker-dependent performance of gH625–siRNA conjugates enables carrier-free brain delivery and prophylaxis against HSV-1 infection
Nectin-1 is a major entry receptor involved in HSV-1 infection of the brain, making its suppression before viral exposure a potential host-directed preventive strategy. siRNA can reversibly reduce Nectin-1 expression,...
Yi-Wan Geng, Jia-Min Zuo, Yu-Sheng Zhang et al.
· Industrial Chemistry & M... · 0 citations