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Author

Yi Wang

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2 papers indexed here

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Open access Sep 2026

Monocyte inflammation and adaptive immune dysfunction in severe Klebsiella pneumoniae pneumonia

Abstract Severe Klebsiella pneumoniae pneumonia is associated with substantial mortality and is characterized by intense systemic inflammation that coexists with a failure to control infection. The cellular changes underlying the transition from effective host defense to immune dysfunction remain incompletely defined....

Hong-Quan Chen, Xiao-Ling Wang, Xiang Liu et al. · 0 citations
Open access Aug 2026

A single-cell transcriptomic atlas reveals the immune panorama of neonatal sepsis.

Neonatal sepsis remains a leading cause of infant mortality, yet mechanisms driving concurrent hyperinflammation and immunosuppression remain unclear. Here, we perform single-cell RNA sequencing on 26 blood samples from 18 neonates, spanning acute sepsis, convalescence, and healthy controls. We identify 57 cell subtype...

Jie Wang, Ying Chen, Pei-Cen Zou et al. · 0 citations

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