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Yi-Wen Zhang

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Open access Oct 2026

Spica Prunellae attenuates ER stress via GRP78/IRE1α/JNK pathway in CCL4-induced acute liver injury in mice

Objective To evaluate the effects of Spica Prunellae (SP) on CCl4-induced acute liver injury (ALI) in mice and its regulation of the endoplasmic reticulum stress pathway. Methods In the toxicity test, ICR mice were administered SP decoction (2 g/kg, crude herb/mouse weight) by gavage for 10 days. Liver and kidney tissu...

Yan-Jie Wang, Jia-Ping Hao, Jin-Feng Yang et al. · 0 citations

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