Pst and Tat Systems Are Essential for Ehrlichia chaffeensis Intracellular Survival and Regulated by CtrA
Ehrlichia chaffeensis is an obligate intracellular Gram-negative bacterium that infects human monocytes and macrophages, causing human monocytic ehrlichiosis (HME). HME is an emerging and highly threatening tick-borne infectious disease. CtrA functions as the response regulator of the CckA/CtrA two-component regulatory...