Author

Yi-Xiang Huang

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Open access Sep 2026

PCIPG: A comprehensive framework for protein complex identification based on a probabilistic graphical model

PCIPG is presented, a multi-scale probabilistic graph framework that jointly models residues, proteins, interactions and complexes and bridges residue-scale structural cues with interactome-scale organization to enable interpretable and scalable protein complex identification.

Yi-Xiang Huang, Lei Yang, Jiu-Dong Wang et al. · PLoS Computational Biology · 0 citations

Open access Jul 2026

PCIPG2.0: multi-omics fusion and structure-aware graph autoencoding for protein complex identification

PCIPG 2.0 is presented, an unsupervised framework that explicitly addresses two major bottlenecks in PPI-based complex discovery: missing interactions and limited mechanistic specificity.

Yixiang Huang, Jiudong Wang, Lei Yang et al. · Bioinformatics · 0 citations