Open access
Jul 2026
Single-cell and spatial transcriptomic landscapes reveal PIGT as a pivotal regulator of immunometabolic remodeling in colorectal cancer liver metastasis
Integrative multi-omics and experimental analyses identify PIGT as a central regulator bridging tumor metabolism and immune modulation in CRLM and highlight PIGT as a promising prognostic biomarker and potential therapeutic target for metastatic colorectal cancer.
Mengzhu Yan, Yi-Xing Li, Yun Liu et al.
· Functional & Integrative Gen... · 1 citation