Sep 2026
Machine Learning-Assisted Multiplexed and Ultrasensitive Biosensing of Pathogenic Bacteria based on a Tt Ago-Powered Autocatalytic Nucleic Acid Circuit and Encoded SERS Tags
Programmable nucleases have obtained widespread application in the field of pathogen detection, yet they face considerable challenges in multiplex detection. As a sister technology to CRISPR/Cas systems, Argonaute proteins (Ago) possess programmability, sequence specificity, and multi-turnover capability, rendering t...
Xi-Ru Zhang, Man-Yan Qiu, Jia-Xi Huang et al.
· Analytical Chemistry · 0 citations