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Author

Yi-Ying Zhang

2 papers indexed here

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Open access Sep 2026

Genetically supported targets and drug repurposing for sleep disorders: a Mendelian randomization systematic study.

Sleep disorders present major public health issues because of their associations with chronic diseases. Despite extensive research efforts, the underlying biological mechanisms remain inadequately understood. We performed bidirectional two-sample Mendelian randomization (MR) to investigate relationships between sleep d...

Zi-Yu Wang, Miao Zhang, Cong Liu et al. · 0 citations
Aug 2026

Single-cell transcriptomic analysis reveals systemic immune dysregulation and identifies PLEK as a candidate hub gene associated with CD8+ T-cell activation in myasthenia gravis.

Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody-mediated neuromuscular dysfunction, but the systemic immune landscape and underlying mechanisms remain unclear. Here we analyzed single-cell RNA-seq data from peripheral blood mononuclear cells of MG patients and healthy controls to characterize...

Jing-Nan Jin, Zi-Hong Chen, Yi-Ying Zhang et al. · 0 citations

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