Author

Yi Zhang

3 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Aug 2026

CD73 inhibition overcomes adaptive immune resistance to PARP inhibition in models of prostate cancer

Metastatic castration-resistant prostate cancer (mCRPC) remains a leading cause of cancer-related mortality in men. Although poly(ADP-ribose) polymerase (PARP) inhibitors are approved for mCRPC patients with homologous recombination repair (HRR) deficiencies, clinical trials combining olaparib with PD-1/PD-L1 inhibitor...

Ping Xie, Ren-Qiang Ma, Ming-Hui Zhang et al. · Journal of Clinical Investig... · 0 citations

Aug 2026

H2AFY2 suppresses exhaustion and enhances antitumor activity of CAR-T cells through transcriptional and epigenetic modifications.

Chimeric antigen receptor (CAR)-T cell exhaustion constitutes a critical barrier to sustained antitumor efficacy. Through transcriptomic analysis of CAR-T cells from patients with lymphoma, we identified the histone variant macroH2A2 (H2AFY2) as a critical regulator of T cell exhaustion-a finding consistently observed...

C. Li, Qian Wang, Qi-Tai Zhao et al. · Cancer immunology research · 0 citations

Open access Sep 2026

Myeloid-derived suppressor cells confer stemness to esophageal cancer cells through the HNF1A/CXCL1 signaling axis

Our previous work established that myeloid-derived suppressor cells (MDSCs) were abundant in human esophageal squamous cell carcinoma (ESCC) and correlated with adverse prognosis. Yet their direct, T cell-independent impact on tumor propagation remains undefined. Here, we show that MDSCs accelerate ESCC growth in bot...

Guo-Hui Qin, Ping-Chuan Ma, Sha-Sha Liu et al. · Cancer Immunology and Immuno... · 0 citations