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Aug 2026

MFN2-mediated remodelling of ER-mitochondria communication alleviates ochratoxin A-induced hepatocyte ferroptosis by enhancing mitophagy.

Mycotoxins are ubiquitous environmental contaminants that widely occur throughout ecosystems and the food chain, posing persistent threats to environmental safety and public health. Ochratoxin A (OTA) is a widespread and chemically stable mycotoxin with recognized hepatotoxicity, yet the mechanisms linking OTA exposure...

Zi-Yan Hu, Rui-Qi Liu, Yu-Xuan Ouyang et al. · 0 citations
Open access Aug 2026

A New Insight into the Mechanism of DEHP-Induced Hepatotoxicity in Adolescent Mice: Triggering Hepatic Lipid Accumulation by Targeting GRP75-Dependent MAM Formation

Di(2-ethylhexyl) phthalate (DEHP) is widely acknowledged as a prevalent environmental pollutant, mainly due to its extensive use in plastics. This widespread application has resulted in its presence in air, soil, water, and various food items, as well as in agricultural products and tissues of both humans and anima...

Hao Zhang, Jia-Jing Cui, Bing Sun et al. · 0 citations

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