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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Yi Zhou

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Open access Aug 2026

Ergosterol remodeling by the MARVEL protein Mrv6 links genotoxic stress adaptation to virulence in Candida albicans.

How fungal pathogens coordinate genotoxic stress responses with membrane homeostasis to sustain cellular signaling remains poorly understood. In this study, we characterize Mrv6, a MARVEL domain-containing membrane protein that is prominently induced by genotoxic stress. Intriguingly, rather than functioning as a canon...

Wenxia Gao, Yi Zhou, Suna Jiang et al. · 0 citations
Open access Aug 2026

The genotoxic stress-inducible gene GEI1(Orf19.3109) is a repressor of virulence in Candida albicans

The findings uncouple transcriptional induction from conventional DNA repair functions and reveal a novel regulatory checkpoint where GEI1 links genotoxic stress signaling to the suppression of key pathogenic traits, highlighting a complex strategy by which C. albicans balances stress adaptation and virulence control.

Yi Zhou, Wenxia Gao, Yuting Feng et al. · 0 citations

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