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Yi-Zhun Zhu

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Aug 2026

Transcriptomic Characterisation and Diagnostic Performance of S100A8, S100A9, S100B, and ENO2 (Neuron-Specific Enolase) in Pediatric Bacterial Meningitis: A Cross-Platform Re-analysis of Two Public GEO Datasets

Background: Bacterial meningitis (BM) remains a leading cause of mortality and neurological disability in children worldwide. Despite advances in antimicrobial therapy, neurological sequelae persist in up to 50% of survivors. Host-blood transcriptomic biomarkers have shown promise for early differentiation of bacterial...

Zhe-Jiang Ding, Shu-Min Feng, Zhong-Liang Li et al. · 0 citations
Sep 2026

Isoschaftoside improves white matter injury via TREM2-mediated phagocytosis and anti-inflammatory effects.

Experimental evidence is provided supporting ISO as a potential therapeutic agent for vascular cognitive impairment by dose-dependently improving cognitive function and attenuated demyelination in white matter regions of BCAS mice.

Cheng-Gang Li, Yu-Hao Xu, Huai-Ping Tang et al. · 0 citations

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