Author

Yi-Zi Jin

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Open access Sep 2026

The TUBA1B–G3BP2 Axis Sustains p65 Transcriptional Activity to Promote Hepatocellular Carcinoma Progression

ABSTRACT Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality, yet mechanisms sustaining malignant progression remain incompletely defined. Integrative analyses across multiple HCC cohorts identified TUBA1B as one of the most consistently upregulated tubulin isotypes whose high expression associates wi...

Feng Lin, Hechun Lin, Junming Yu et al. · Advancement of science · 0 citations

Aug 2026

AKAP13 regulates GLI1/ULK1 axis and drive tumor resistance to next-generation HER2-targeted therapies

It is reported that primary HER2-specific targeted therapy (tucatinib) resistant or sensitive breast cancers derived from clinical trial patients exhibited differential protein profiles and was proposed as a promising therapeutic strategy for HER2-positive breast cancer.

Qing Guo, Xinyu Chen, Lin-Feng Wu et al. · Oncogene · 0 citations