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Yi-Zong Lee

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Open access Aug 2026

The conserved bridging domain on HCV E1E2 glycoprotein complex is targeted by neutralizing antibodies from diverse lineages.

Describing the genetic, structural, functional, and epitope features of 25 BD-directed nAbs isolated from HCV-infected individuals or immunized macaques underscores BD as a promising target for rational HCV vaccine design.

Fang Chen, Yen Thi Kim Nguyen, Yi-Zong Lee et al. · Cell Reports · 0 citations