Author

Yichi Zhang

2 papers indexed here

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Review Open access Aug 2026

Immunometabolic Remodeling in Osteosarcopenia: Inflammaging, Mitochondrial Dysfunction, Gut-Derived Metabolites and Therapeutic Opportunities

Osteosarcopenia—defined as the coexistence of sarcopenia and osteoporosis—is increasingly recognized as a clinically important geriatric syndrome associated with falls, fractures, frailty, disability, and mortality. Beyond the simple coexistence of bone and muscle loss, emerging data suggest that osteosarcopenia may re...

Yichi Zhang, Yun-Tao Li, Xun Luo et al. · Metabolites · 0 citations

Open access Aug 2026

Senescence-related immunosuppressive gene MFAP2 orchestrates stromal-immune crosstalk and immunotherapy resistance in gastric cancer

MFAP2 is a hub SRIG linking eCAFs, ECM remodeling, and immune escape in GC, which serves as a reliable prognostic and ICI resistance predictor and potential therapeutic target, providing a basis for precision therapy in GC.

Yi-Chan Hu, Liao-Xiang Zhu, Lijun Zhou et al. · BMC Cancer · 0 citations