Lead optimization, the systematic refinement of therapeutic compounds through iterative structural modification, faces a dual challenge in modern drug discovery: navigating astronomically vast molecular design spaces while balancing conflicting demands on potency, pharmacokinetics, and safety. We present MASCOT (Multi-...
ETHNOPHARMACOLOGICAL RELEVANCE
Coicis Semen is a classic example of a resource used both as food and medicine. In traditional Chinese medicine, it is known for several functions: promoting diuresis, resolving dampness, strengthening the spleen, stopping diarrhea, draining pus, and removing toxins. For a long time, it h...
Jia-li Ma, Qianqian Yin, Yi-jing Zhou et al.· Journal of Ethnopharmacology· 0 citations
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