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Aug 2026

Downregulation of miR-33a-5p regulates TNF-α/NF-κB signaling and is associated with reduced diabetic neuropathic pain through targeting SIRT6.

BACKGROUND The pathogenesis of diabetic neuropathic pain (DNP) remains unclear, with neuroinflammation mediated by abnormal TNF-α/NF-κB pathway activation being a key factor. This study aims to elucidate how this pathway contributes to DNP. METHODS miR-33a-5p levels were measured via qPCR in the serum of diabetic pat...

Wenjun Li, Yimei Li, Yong-Xin Wang · 0 citations
Review Open access Jan 2026

Associations of Geriatric Nutritional Risk Index and Prognostic Nutritional Index With All‐Cause and Cardiovascular Mortality in DKD: NHANES 1999–2018

Background Malnutrition and immune status significantly influence the prognosis of diabetic kidney disease (DKD). However, the correlations between two novel nutritional–immune indices—geriatric nutritional risk index (GNRI) and prognostic nutritional index (PNI)—and the risk of all‐cause mortality (ACM) and cardiovasc...

Yimei Li, Jimei Song, Li-Ying Liu et al. · 0 citations

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