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Yin-Ping Wang

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Review Open access Sep 2026

Breaking the deadlock of metallo-β-lactamases: evidence and prospects for Aztreonam/Avibactam

ABSTRACT Multidrug-resistant Gram-negative bacteria pose a significant threat to global public health, with resistance mediated by metallo-β-lactamases being particularly prominent. Aztreonam/avibactam (AZA), a novel β-lactam/β-lactamase inhibitor combination, had been approved in China and the European Union for treat...

Jun-Xin Zhou, Rui Weng, Yi-Ning Ye et al. · 0 citations

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