Author

Yin Xu

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Open access Sep 2026

Integrative Identification of Candidate Protein Targets and Compounds for Dystonia Using Mendelian Randomization, Single-Cell RNA Sequencing, and Network Pharmacology

Background: Dystonia is a severe neurological disorder with enigmatic pathogenesis. Current treatment options are limited in preventing the disease progression, underscoring the urgent need for new targeted therapeutic agents to develop more effective therapies. Methods: We performed a proteome-wide Mendelian randomiza...

Lin Chen, Ming-Juan Fang, Nan Cheng et al. · Genes · 0 citations

Open access Aug 2026

Genome-Wide Association Summary Statistics-Based Genetic Mapping of Brain Functional and Structural Networks in Type 2 Diabetes Mellitus and Its Complications.

It is revealed that the genetically predisposed higher risk of diabetic maculopathy was associated with increased salience network connectivity, shedding light on the neural drivers of diabetic pathologies.

Lin Chen, Hsin-Yu Hsieh, Nan Cheng et al. · Brain Research Bulletin · 0 citations