Author

Ying-Fu Li

3 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Oct 2026

An Integrated DNA Origami-Based RNA Degrader for Targeted Degradation of Oncogenic Mutant KRAS mRNA

Targeting mutant KRAS represents a critical yet unmet therapeutic challenge across multiple malignancies, as the structural diversity of oncogenic variants and absence of druggable pockets have impeded the development of effective small-molecule inhibitors. Here, we report an integrated RNA degrader system constructe...

Ying-Fu Li, Qing Huang, Pin-Ru Chen et al. · ACS Pharmacology & Trans... · 0 citations

Open access Sep 2026

Competitive SELEX Strategy for High-Affinity Aptamer Isolation and Enhanced Biosensing.

Aptamers, with their high specificity and affinity, are invaluable for diagnostics and therapeutics. However, conventional SELEX (Systematic Evolution of Ligands by Exponential Enrichment) often favors abundant low-affinity sequences, limiting the isolation of rare, high-affinity candidates. To overcome this challenge,...

Jiu-Xing Li, Jia-Xuan Xiao, Jimmy Gu et al. · Small · 0 citations

Open access Sep 2026

Lab-in-a-Tube System Integrating Hierarchically Wrinkled Electrodes and DNAzyme-Functionalized Beads for Diagnosis of Clostridioides difficile Infection.

The diagnosis of bacterial infections remains slow because many existing methods rely on enrichment steps such as nucleic acid amplification or growth culture. RNA-cleaving DNAzymes offer a promising route to accelerate bacterial diagnosis because they can be selected and programmed to specifically recognize disease-ca...

Survanshu Saxena, Soyeon Lee, Youngeun Choi et al. · Advances in Materials · 0 citations