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Author

Ying-Hong Long

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Sep 2026

Discovery of a Broad-Spectrum Antiviral Compound against Porcine Reproductive and Respiratory Syndrome Virus

Porcine reproductive and respiratory syndrome virus (PRRSV) causes substantial economic losses to the swine industry, while vaccine-based control remains challenges. The study performed structure−activity relationship (SAR)-guided optimization of tylvalosin, yielding 42 novel derivatives. Compound V-28 exhibited the...

Xiao-Pei Yang, Ru-Meng Ma, Ying-Hong Long et al. · 0 citations

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