Author

Ying-Jie Wang

2 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Review Open access Aug 2026

Protein farnesylation: from molecular mechanisms to therapeutic targeting in cancer, aging, and beyond

Protein farnesylation, catalyzed by farnesyltransferase (FTase), covalently attaches a 15-carbon farnesyl lipid to cysteine residues within C-terminal CaaX motifs. This modification governs the subcellular localization, protein–protein interactions, and activity of diverse eukaryotic proteins, including Ras GTPases, nu...

Jiacheng Lou, Dan Zhang, Ying-Jie Wang · Frontiers in Pharmacology · 0 citations

Open access Aug 2026

Multi-omics integration identifies APOE as a metabolic regulator of macrophage-fibroblast crosstalk in idiopathic pulmonary fibrosis

A two-sample Mendelian randomization analysis indicated that genetic liability to AD is associated with a lower risk of developing IPF, and APOE functions as a vital metabolic barrier against pro-fibrotic macrophage polarization in the lung.

Bing Bai, Le Chang, Zhi Cheng et al. · Frontiers in Immunology · 0 citations