Aug 2026
Robust annotation and discovery of novel cell types in single-cell ATAC-seq data through cross-modal reference alignment.
CARA is introduced, a cross-omics Bayesian framework that transfers cell type knowledge from scRNA-seq to scATAC-seq and detects novel cell types in single-cell DNA methylation data, demonstrating seamless extensibility to new modalities.
Lan Cao, Wenhao Zhang, Feng Zhou et al.
· Genome Research · 0 citations