Author

Ying Wang

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Jul 2026

hIMB1636-LDM, a novel anti-TROP2 ADC, exerts potent antitumor efficacy in pancreatic cancer via direct cytotoxicity and immune activation.

HIMB1636-LDM exerts potent antitumor activity through a dual mechanism combining targeted cytotoxicity and ICD induction, and was for the first time found to possess the ability to trigger immunogenic cell death (ICD).

Dan-dan Zhou, Dong-Cheng Jiang, Xiao-Rui Xu et al. · Biochemical Pharmacology · 0 citations