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Ying-Wen Dai

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Open access Sep 2026

Base and Nucleophilic Catalysis Enables Formal [3+2] Cycloaddition of Alkynyl Diazoketones and Aminomalonates: Access to γ,γ-Disubstituted 3-Pyrrolin-2-ones.

A formal [3+2] cycloaddition of alkynyl diazoketones with aminomalonates has been developed, providing rapid access to highly substituted γ,γ-disubstituted 3-pyrrolin-2-ones. This transformation proceeds under mild conditions with broad substrate scope and good functional-group tolerance, providing a practical approach...

Xin Ji, Ying-Wen Dai, Shu-Yu Yao et al. · 0 citations

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