Aug 2026
Erchen Decoction Alleviates MAFLD by Regulating MFN2-mediated Endoplasmic Reticulum Stress.
EC exerts significant protective effects against MAFLD by upregulating the MFN2/ERMIT2 axis and suppressing the PERK, eIF2α, and ATF4 ERS pathway, suggesting a restorative effect on calcium handling, maintains ER homeostasis, and reduces hepatocyte injury, highlighting EC as a promising therapeutic candidate for MAFLD.
Qing-Xuan He, Meng-Zhen Wang, Xu Wang et al.
· Endocrine, Metabolic & Immun... · 0 citations