Aug 2026
The O-glycosylation of SH3PX1 accelerates the progression of lung adenocarcinoma by modulating cell proliferation and glycolysis.
Findings provide that SH3PX1 acts as a regulator of LUAD malignancy through GALNT2-mediated O-glycosylation and stabilization, suggesting that targeting SH3PX1 may represent a potential therapeutic strategy for LUAD.
Si-Yao Wang, Yingqi Tang, Ye-Gang Ma et al.
· Cellular Signalling · 0 citations