Design and Synthesis of Potential Quinoline-Based SDH Inhibitors Inspired by Quinine Alkaloids with Activity against Phytopathogenic Fungi and Bacteria.
In pursuit of environmentally friendly agrochemicals, we employed the natural quinine alkaloid scaffold as a lead for the design and synthesis of three series of structurally diverse quinine derivatives and systematically evaluated their in vitro antibacterial and antifungal activities. Among them, compounds Ka9 and Ka...