Review
Open access
Jul 2026
Pharmacological Effects and Molecular Mechanisms of Lignans in the Treatment of Alzheimer’s Disease
Alzheimer’s disease (AD) is a complex, multifactorial neurodegenerative disorder whose core pathological hallmarks include Aβ aggregation, tau hyperphosphorylation, chronic neuroinflammation, oxidative stress, mitochondrial dysfunction, and gut microbiota dysbiosis. Lignans, a class of naturally occurring polyphenolic...
Li-Meng Sun, Xin-An Zhu, Chunyan Fan et al.
· Molecules · 0 citations