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Author

Yiran Zheng

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Open access Oct 2026

Lipid-engineered antibody-based therapeutics target inflamed joints and lymph nodes to enhance rheumatoid arthritis treatment.

Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation and joint damage. Although antibody (Ab)-based biologic disease-modifying anti-rheumatic drugs (bDMARDs) have transformed RA treatment, their efficacy remains limited in many patients. Here, we conjugate Ab-based bDMARDs wi...

Lei Zhao, Shan An, Meng-Qian Gao et al. · 0 citations
Open access Jul 2026

NOD1/2 signaling in macrophages drives adaptive immune resistance in cancer

NOD1/2 is defined as a novel innate immune checkpoint that orchestrates therapy-induced adaptive resistance and highlight this pathway as a promising target to overcome treatment resistance in refractory cancers.

Xi-Duan Wei, Li Yang, Yuting Wang et al. · 0 citations

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