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Author

Yiwen Liao

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Open access Aug 2026

Cyclic di-GMP directly reprograms the multidrug resistance machinery via UspG-mediated sequestration of RamR in Klebsiella

This study identifies that upon the elevation of intracellular c-di-GMP levels induced by antibiotic treatmen, the universal stress protein UspG serves as a cryptic, direct c-di-GMP effector in extended-spectrum beta-lactamase (ESBL)-producing strain K. pneumoniae, and indicates that UspG is functionally conserved acro...

Xiao-Xiao Liu, Mingfang Wang, Yi-Kai Fu et al. · 0 citations

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