Case report
Open access
Jul 2026
Compound heterozygous variants in PATL2 cause oocyte germinal vesicle arrest associated with primary infertility: a case report and literature review
GV arrest caused by PATL2 defects cannot be overcome by conventional or optimized IVF protocols even with individualized COH, and Donor-oocyte IVF remains the ultimate effective strategy for pregnancy in such patients.
Xiaoxia Song, Lei Yan, Yiwen Zhang et al.
· Frontiers in Medicine · 0 citations