N-linked glycosylation of the EP3α receptor is essential for the regulation of platelet homeostasis
Platelet activation and aggregation represent pivotal events in hemostasis and thrombosis. Prostaglandin E2 (PGE 2 ) receptor subtype 3 (EP3), the most abundantly expressed PGE 2 receptor in platelets, regulates platelet activation. Yet, the underlying mechanisms remain incompletely defined. Glycosylation, one...