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Open access Sep 2026

High‐Concordance Detection Across Diverse Biospecimens EGFR Mutation in a Large‐Scale NSCLC Cohort Using Droplet Digital PCR and Next‐Generation Sequencing

Accurate detection and quantification of EGFR mutations are essential for molecular stratification in non‐small cell lung cancer (NSCLC). While next‐generation sequencing (NGS) enables comprehensive genomic profiling, droplet digital PCR (ddPCR) offers high sensitivity for predefined mutations. Large‐scale evaluati...

Ming Liu, Lin-Ping Lu, Qifang Lei et al. · 0 citations
Aug 2026

Multiplex digital PCR for rapid quantitative detection and dynamic monitoring of respiratory pathogens in bronchoalveolar lavage fluid.

Lower respiratory tract infections (LRTIs) remain a leading cause of mortality worldwide. Rapid and comprehensive etiological diagnosis is critical yet challenging: existing approaches, from culture to multiplex PCR and mNGS, carry distinct limitations in one or more of turnaround time, sensitivity, cost, or quantitati...

Fang Wang, T. Yuan, Chianru Tan et al. · 0 citations

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