Author

Yonghong He

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#machine learning Preprint Sep 2026

SpaFactor: Lightweight Spatial Context-Aware Gene Program Modeling for Histology-to-Transcriptomics Inference

Spatial transcriptomics (ST) profiles gene expression within tissue architecture, but its cost and experimental complexity limit routine use. Predicting spatial expression from routinely available hematoxylin and eosin (HE) images therefore offers a scalable alternative. However, conventional methods often fit high-dim...

Shi-Ting Ruan, Xi-Tong Ling, Qi-Ming He et al. · 0 citations

Preprint Aug 2026

DeCo-MIL: Debiased Counterfactual Reasoning for Long-Tailed Whole Slide Image Analysis

Multiple instance learning (MIL) is widely used for weakly supervised whole slide image (WSI) analysis. However, under long-tailed distributions, MIL-based WSI analysis faces a nested dual long-tail: an inter-slide class long tail and an intra-slide long tail of instance-level discriminative evidence. The two long tail...

Xiao-Xiao Li, Xi-Tong Ling, Jiawen Li et al. · 0 citations

Review Aug 2026

ConRub-Med: Reinforcement Learning with Consensus Rubrics for Open-Ended Medical Question Answering

ConRub-Med is introduced to preserve useful distinctions as rubric feedback moves from construction to policy optimization, and ranks first on six of nine benchmarks and achieves the highest medical and generalization averages.

Taojie Zhu, Yuan Xia, Tao Sun et al. · 0 citations