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Yong-Hui Jiang

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Open access Oct 2026

Multi-omic profiling reveals impaired luteal resolution and CHK2-regulated inflammation in ovarian aging

The ovary ages earlier than most other organs, but the molecular mechanisms that drive this decline remain unclear. To gain more insight into this process, we profiled ovaries from young and reproductively aged mice after synchronized ovulation and found that aging was marked by the accumulation of luteal cells with in...

Liu-Bin Yang, Zhong-Wei Sun, Xin-Long Luo et al. · 0 citations
Open access Jul 2026

The linker histone H1.4 condenses chromatin in maturing postmitotic neurons

The expression of H1f4 mRNA and H1.4 protein in the brains of male and female mice across postnatal development is characterized and it is shown that developmental maturation of chromatin compaction in cerebellar granule neurons is disrupted in H1f2/H1f4 double knockout mice.

Andrew I. Aldridge, Martine W. Tremblay, Vijyendra Ramesh et al. · 0 citations

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