Open access
Aug 2026
The EV-A71 RNA-binding protein Matrin 3 facilitates viral replication by stabilizing viral RNA via ZDHHC20-mediated palmitoylation.
A mechanistic pathway by which EV-A71 co-opts MATR3 through condensate formation and palmitoylation to stabilize its genomic RNA and promote viral replication is delineated, and a comprehensive profiling dataset of host proteins associated with EV-A71 RNA is provided.
Xiaoyan Zuo, Yong-Jun Chen, Xia Xiao et al.
· Proceedings of the National... · 0 citations