Open access
Sep 2026
USP18 Serves as a Key Mediator of cGAS‐STING for Cardiac Aging in Diabetes
ABSTRACT Diabetes accelerates cardiac aging, but the molecular mechanisms that link metabolic stress to myocardial senescence remain insufficiently defined. This study investigated factors driving diabetes‐associated cardiac aging with a focus on the role of USP18. Type 2 diabetes mellitus (T2DM) was induced in mice us...
Xun-Xi Deng, Z. Yin, Shi Tai et al.
· Cell Biochemistry and Functi... · 0 citations