Author

Yong-Li Zhan

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Review Open access Sep 2026

Efficacy and safety of GLP-1RAs, SGLT2is, and nsMRAs for cardiovascular and renal outcomes in T2DM with CKD: a systematic review and network meta-analysis

Objective To compare cardiovascular and renal benefits and safety of GLP-1RAs, SGLT2is, and nsMRAs in T2D-CKD using network meta-analysis. Methods RCTs published through 7 August 2026 were systematically identified. A frequentist random-effects network meta-analysis was performed. Evidence certainty was assessed with C...

Hong-Li Chen, Xue-Jie Wu, M. Yuan et al. · Frontiers in Endocrinology · 0 citations

Sep 2026

Transcriptomics-informed systems toxicology prioritizes candidate links between endocrine-disrupting chemicals and chronic kidney disease.

A transcriptomics-informed systems toxicology workflow to prioritize CKD-relevant candidate genes associated with predicted human protein targets of 12 selected representative EDCs compiled from ChEMBL, SwissTargetPrediction and PharmMapper, which prioritizes an externally evaluated FOS/MDK diagnostic-candidate panel a...

Fei-Hong Ren, Han Li, Xu-Shan Lan et al. · Environmental Pollution · 0 citations

Review Open access Jul 2026

Emerging roles of SIRT6 and its modulators in kidney diseases.

An overview of the sirtuin family, systematically characterize the enzymatic activities and critical biological functions of SIRT6, and discuss its molecular mechanisms across various kidney diseases, focusing on its cell type-specific functions are provided.

Fei-Hong Ren, Yudian Wang, Yufei Zhang et al. · Cell Death Discovery · 0 citations